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Nitrofurantoin

Chemical name: 1-{[(5-nitrofuran-2-yl)methylidene]amino}imidazolidine-2,4-dione
CAS: 67-20-9
Structural formula:

Molecular formula: C8H6N4O5
Molecular weight: 238.16
Authentication code: Guo Yao Zhun Zi H37022205
Specification:
A: Accord with China Pharmacopoeia 2010 edition
Appearance: Yellow crystal powder
Assay: 98.0~102.0%
Loss on drying: Not more than 1.0%
Reidue on ignition: Not more than 0.1%
Acidity: 5.5~7.0
Related substances: ≤1%
Nitrofurazone: ≤ 0.01%
B: Accord with Europe Pharmacopoeia (EP7) edition
Appearance: A yellow crystalline powder or yellow crystals
Assay: 98.0~102.0%
Loss on drying: Not more than 1.0%
Sulphated ash: Not more than 0.1%
Related substance: Not more than 1.0%
C: Accord with United States Pharmacopoeia 35 edition
Appearance: A lemon-yellow crystalline powder.
Assay: 98.0~102.0%
Loss on drying: Not more than 1.0%
Limit of Nitrofurfural Diacetate: not more than 1.0%
Limit of Nitrofurazone: not more than 0.01%
Application: Used for urinary tract infections resulted by sensitive bacteria, like pyelonephritis, urinary tract infection, cystitis and prostatitis.

 
 
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